b3A Mutations Associated with Hermansky-Pudlak Syndrome type 2

Map of beta-3A Subunit of the AP-3 Complex Gene Mutations Associated with HPS

This figure shows the coding region of the b3A subunit (1094 amino acids). Red is the amino-terminal domain, blue is the hinge region, and yellow is the orange is the carboxy-terminal domain. This subunit is part of the heterotetrameric AP-3 complex.

References on gene structure:

Dell'Angelica, E. C., Ooi, C. E., Bonifacio, J. S. b3A-adaptin, a subunit of the adaptor-like complex AP-3. Journal of Biological Chemistry 272:15078-15084, 1997. [Link to article (PubMed)]


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Last changed July 16, 1999.