Poster presentation, P74

Official XXIst International Pigment Cell Conference website - 21-24 Sept 2011, Bordeaux - France | updated: September 04 2011

Treatment of vitiligo hands by recellsystem associated with excimer lamp

SPEAKER M. Pascal #whois submiter ?
AUTHOR(s) M. Pascal, L. Valente

BACKGROUND: Vitiligo hands is a common localisation but most of the time, medical treatment (UVB TL01,excimer lamp or laser, tacrolimus or corticosteroîds) is not efficient. Many surgeons recommand surgical procedures as punch grafting, suction blister grafting, split-thickness skin grafting, cultured melanocytes or noncultured melanocytes transplantation. A preliminary report has been published in 2010 August about Recell system (non cultured autologous epidermal suspension) for the treatment of one case with a stable vitiligo hands by Cervelli and collegues (Department of Plastic and Reconstructive Surgery, Roma University Italy). An excellent repigmentation has been noticed in this case. The authors consider this procedure as a simple and safe method. OBJECTIVE: The goal of this study was to find a easier technic to separate melanocytes from epidermis before grafting and to avoid big loss of melanocytes after classic skin dermabrasion. METHODS: One patient with a vitiligo hands resistant to uvb TL01 has been selected. All the vitiligo areas are treated by liquid nitrogen 24h before the session. A thin skin sample is taken from thigh and treated by RECELL. Keratinocytes and melanocytes suspension is injected in blisters. After healing the skin is exposed to excimer lamp (QUANTEL) two times a week during 6 months. RESULTS: A repigmentation of 70% of treated area has been observed. No hypertrophic or cheloïd have been noticed. CONCLUSION: This procedure of melanocytes obtained by RECELL system injected in blisters seems to be a good and safe method for treating difficult areas as vitiligo hands.



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