Oral communication, iL41

Official XXIst International Pigment Cell Conference website - 21-24 Sept 2011, Bordeaux - France | updated: September 04 2011

Congenital Melanocytic Nevus Syndrome: clinical and genetic aspects

The study of rare congenital diseases frequently illuminates the mechanisms governing normal fetal development, as well as commoner acquired diseases. The study of large/multiple congenital melanocytic naevi (CMN) has the potential to contribute to both areas of knowledge, acting as an example of abnormal neural crest development and as a predisposition to malignant melanoma. Ongoing clinical characterisation of associated features of CMN has recently resulted in the proposal of the term CMN syndrome, and the underlying genetics are currently being investigated using a large cohort of patients from Great Ormond Street Hospital.

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